Chiropractic, Medication, and Self-Care for Neck Pain Sponsor      Health Services Research Administration (HRSA) Principal Investigator      Gert Bronfort, DC, PhD, Northwestern Health Sciences University Berman Center Investigator      Richard Grimm, MD, PhD Description This randomized, observer-blinded clinical trial compares the relative efficacy of chiropractic spinal manipulation, prescription medication, and self-care advice for recent-onset neck pain. Efficacy is compared in the short term (after 6 weeks) and long term (after 52 weeks), using patient ratings as the main outcome measure. Please visit Northwestern Health Sciences University (NWHSU) for more information. Manipulation, Exercise, and Self-care for Low Back Pain Sponsor      Health Services Research Administration (HRSA) Principal Investigator      Gert Bronfort, DC, PhD, Northwestern Health Sciences University Berman Center Investigator      Richard Grimm, MD, PhD Description This is a randomized, observer-blinded clinical trial comparing chiropractic spinal manipulation, rehabilitative exercise, and self-care education for patients with chronic low back pain. Interventions are compared for their short- and long-term efficacy, as well as their cost-effectiveness and cost-utility. Please visit Northwestern Health Sciences University (NWHSU) for more information. Chiropractic and Exercise for Seniors with Low Back Pain Sponsor      Health Services Research Administration (HRSA) Principal Investigator      Gert Bronfort, DC, PhD, Northwestern Health Sciences University Berman Center Iinvestigator      Richard Grimm, MD, PhD Description This study seeks to identify effective therapies for low back pain, and to discover the best methods for enhancing health and functional capacity, in patients 65 years of age and older, with low back pain of more than 6 weeks duration. The study compares three treatments for reduction in patient ratings of low back pain after 12 weeks of therapy and one year after therapy ends. The three treatments are chiropractic manipulation and home exercise, supervised rehabilitative exercise and home exercise, and home exercise alone. Chiropractic and Exercise for Seniors with Neck Pain Sponsor      Health Services Research Administration (HRSA) Principal Investigator      Gert Bronfort, DC, PhD, Northwestern Health Sciences University Berman Center Investigator      Richard Grimm, MD, PhD Description This study identifies effective therapies for patients 65 years and older who suffer with chronic neck pain to ameliorate the pain and to enhance their functional capacity. The study compares chiropractic treatment and home exercise, supervised rehabilitative exercise and home exercise, and home exercise alone, for reduction of patient-reported neck pain. Manipulation, Exercise, and Self-care for Chronic Neck Pain Sponsor      Health Services Research Administration (HRSA) Principal Investigator Gert Bronfort, DC, PhD, Northwestern Health Sciences University Berman Center Investigator      Richard Grimm, MD, PhD Description This study compares rehabilitative exercise, chiropractic spinal manipulation combined with rehabilitative exercise, and self-care education in reduction of patients’ self reports of neck pain after three and nine months of treatment. The study also compares the cost-effectiveness and cost utility of the treatments, evaluates changes in cervical spine function, examines associations between cervical function and patient-rated outcomes, and identifies predictors of outcome. Please visit Northwestern Health Sciences University (NWHSU) for more information.